NSAIDs and Breastfeeding: Safe Pain Relief for Nursing Moms

Feeling sore after a C‑section or dealing with a migraine while you’re nursing? You don’t have to quit the pain reliever you trust. Many over‑the‑counter NSAIDs (non‑steroidal anti‑inflammatory drugs) are considered low‑risk for babies, but not all are created equal. Here’s a quick rundown of what’s fine, what to watch, and how to keep both you and your infant safe.

Common NSAIDs and Their Safety Profiles

Ibuprofen (Advil, Motrin) tops the list. Studies show only tiny amounts pass into breast milk, and infants tolerate it well. The typical adult dose (200‑400 mg every 4‑6 hours) is safe for most nursing mothers. Just avoid exceeding 1,200 mg per day unless your doctor says otherwise.

Naproxen (Aleve) is another option, but it stays in the body longer. The drug’s half‑life means a slightly higher milk concentration, though still under the “unsafe” threshold. Stick to the lowest effective dose (220 mg every 8‑12 hours) and watch for any fussiness in your baby.

Aspirin should be used with caution. Low‑dose “baby aspirin” (81 mg) is sometimes prescribed for heart health, and the amount that reaches milk is minimal. However, regular‑strength aspirin (325 mg or more) can increase bleeding risk for the infant, especially if the baby is premature. Talk to your pediatrician before reaching for a bottle.

Ketoprofen and Diclofenac are less common in the U.S., but they’re used abroad for joint pain. Data on lactation is limited, and the few reports suggest higher milk levels. Unless you have a specialist’s clearance, it’s safer to choose ibuprofen or naproxen.

Practical Tips for Using NSAIDs While Nursing

Timing matters. Take your NSAID right after a feeding or just before you plan to go a few hours without nursing. This way, the peak drug level in your milk will have passed by the next feed.

Stay hydrated. NSAIDs can irritate the stomach lining, and dehydration can worsen that. A glass of water with each dose helps keep your gut happy and supports milk production.

Watch your baby. A slight increase in drowsiness, irritability, or a change in bowel habits can signal a reaction. If anything feels off, skip the next dose and call your pediatrician.

Don’t mix NSAIDs with other pain relievers unless advised. Combining ibuprofen with acetaminophen is generally okay, but adding aspirin or a prescription anti‑inflammatory can raise the risk of side effects.

Keep a short log. Note the dose, time, and how your baby reacts. Over weeks you’ll spot patterns and can adjust accordingly without guessing.

Lastly, remember that every mom’s situation is different. If you have a health condition that requires higher NSAID doses, or if your baby was born preterm, your doctor might recommend a different approach. The goal is to relieve your pain without compromising your baby’s well‑being.

Bottom line: ibuprofen is the go‑to NSAID for most nursing mothers, naproxen works if you need a longer‑lasting option, and aspirin should be used only under medical supervision. Follow the timing tips, stay observant, and you’ll get through those tough days with minimal hassle.